Risperidone-Induced Mania in Psychoses / 신경정신의학
Journal of Korean Neuropsychiatric Association
;
: 394-399, 1998.
Artigo
em Coreano
| WPRIM
| ID: wpr-111948
ABSTRACT
Risperidone is one of a new class of atypical antipsychotic drug that combines potent dopamine(D2) and serotonin(5-HT2) receptor antagonist properties. In the last few years, there have been several report of risperidone-induced manic symptoms during treatment of schizoaffective disorder or schizophrenia. We report three cases of mania developed in two schizophrenia patients and one amphetamine-induced psychotic disorder which appear to have been precipitated by rispendone. This inducing effect might be attributed to its ability to block postsynaptic 5-HT2 receptors, a property that distinguishes it self from other antipsychotic agents. The blocking of serotonin receptors by risperidone may create a perceived depletion of serotonin similar to that seen in affective disorder and lead to mania. Therefore, we should be cautions in the treatment of psychotic disorder with risperidone.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Transtornos Psicóticos
/
Esquizofrenia
/
Antipsicóticos
/
Transtorno Bipolar
/
Serotonina
/
Receptores de Serotonina
/
Risperidona
/
Transtornos do Humor
Limite:
Humanos
Idioma:
Coreano
Revista:
Journal of Korean Neuropsychiatric Association
Ano de publicação:
1998
Tipo de documento:
Artigo
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