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Risperidone-Induced Mania in Psychoses / 신경정신의학
Journal of Korean Neuropsychiatric Association ; : 394-399, 1998.
Artigo em Coreano | WPRIM | ID: wpr-111948
ABSTRACT
Risperidone is one of a new class of atypical antipsychotic drug that combines potent dopamine(D2) and serotonin(5-HT2) receptor antagonist properties. In the last few years, there have been several report of risperidone-induced manic symptoms during treatment of schizoaffective disorder or schizophrenia. We report three cases of mania developed in two schizophrenia patients and one amphetamine-induced psychotic disorder which appear to have been precipitated by rispendone. This inducing effect might be attributed to its ability to block postsynaptic 5-HT2 receptors, a property that distinguishes it self from other antipsychotic agents. The blocking of serotonin receptors by risperidone may create a perceived depletion of serotonin similar to that seen in affective disorder and lead to mania. Therefore, we should be cautions in the treatment of psychotic disorder with risperidone.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Transtornos Psicóticos / Esquizofrenia / Antipsicóticos / Transtorno Bipolar / Serotonina / Receptores de Serotonina / Risperidona / Transtornos do Humor Limite: Humanos Idioma: Coreano Revista: Journal of Korean Neuropsychiatric Association Ano de publicação: 1998 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Transtornos Psicóticos / Esquizofrenia / Antipsicóticos / Transtorno Bipolar / Serotonina / Receptores de Serotonina / Risperidona / Transtornos do Humor Limite: Humanos Idioma: Coreano Revista: Journal of Korean Neuropsychiatric Association Ano de publicação: 1998 Tipo de documento: Artigo