Three Cases of IgG4-Related Sclerosing Disease in Nasal Cavity
Journal of Rhinology
; : 44-48, 2016.
Article
em Ko
| WPRIM
| ID: wpr-113513
Biblioteca responsável:
WPRO
ABSTRACT
IgG4-related sclerosing disease (IgG4-RSD) is characterized by extensive IgG4-positive plasma cell and T-lymphocyte infiltration of various organs. However, the nasal cavity is an extremely rare site of involvement. The authors experienced three cases of igG4-RSD in the nasal cavity. A 54-year-old woman presented with a nasal cavity mass on endoscopic exam and computed tomography (CT) revealed not only a hypoenhancing mass in the right nasal cavity but also a pituitary gland macroadenoma. Endoscopic removal and endoscopic TSA were performed. A 20-year-old man diagnosed with chronic sinusitis, underwent endoscopic sinus surgery. A 26-year-old woman showed thickening of the nasal septum and cribriform plate, and an infiltrating soft tissue lesion in right the alveolar process on CT and an endoscopic biopsy was performed. Pathologic specimens of all cases showed IgG4-positive plasma cell infiltration, consistent with IgG4-RSD. Serum IgG4 levels were checked in two of the cases, and the results were within normal range. All cases were further treated with methylprednisolone and all showed clinical improvement.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Hipófise
/
Plasmócitos
/
Valores de Referência
/
Sinusite
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Biópsia
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Imunoglobulina G
/
Metilprednisolona
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Linfócitos T
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Osso Etmoide
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Processo Alveolar
Limite:
Adult
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Female
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Humans
Idioma:
Ko
Revista:
Journal of Rhinology
Ano de publicação:
2016
Tipo de documento:
Article