A Solitary Skull Lesion of Syphilitic Osteomyelitis
Journal of Korean Neurosurgical Society
;
: 85-87, 2010.
Artigo
em Inglês
| WPRIM
| ID: wpr-114531
ABSTRACT
We experienced a rare case of solitary syphilitic osteomyelitis of the skull without any other clinical signs or symptoms of syphilis. A 20-year-old man was referred due to intermittent headache and mild tenderness at the right parietal area of the skull with a palpable coin-sized lesion of softened cortical bone. On radiological studies, the lesion was a radiolucent well enhanced mass (17 mm in diameter). The erythrocyte sedimentation rate (52 mm/h) and C-reactive protein (2.24 mg/dL) were elevated on admission. Serum venereal disease research laboratory (VDRL) and Treponema pallidum haemagglutination assay (TPHA) tests were positive. There were no clinical signs or symptoms of syphilis. After treatment with benzathine penicillin, we removed the lesion and performed cranioplasty. The pathologic finding of the skull lesion was fibrous proliferation with lymphoplasmocytic infiltration forming an osteolytic lesion. In addition, a spirochete was identified using the Warthin-starry stain. The polymerase chain reaction study showed a positive band for Treponema pallidum. Solitary osteomyelitis of the skull can be the initial presenting pathological lesion of syphilis.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Osteomielite
/
Penicilina G Benzatina
/
Crânio
/
Spirochaetales
/
Treponema pallidum
/
Sedimentação Sanguínea
/
Proteína C-Reativa
/
Sífilis
/
Infecções Sexualmente Transmissíveis
/
Reação em Cadeia da Polimerase
Limite:
Humanos
Idioma:
Inglês
Revista:
Journal of Korean Neurosurgical Society
Ano de publicação:
2010
Tipo de documento:
Artigo
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