Helicobacter pylori Infection and Peptic Ulcer Disease in Patients with Liver Cirrhosis
The Korean Journal of Internal Medicine
;
: 16-21, 2008.
Artigo
em Inglês
| WPRIM
| ID: wpr-114575
ABSTRACT
BACKGROUND/AIMS:
We investigated the prevalence and relationship of peptic ulcer disease and Helicobacter pylori infection to liver cirrhosis.METHODS:
We examined 288 patients with liver cirrhosis, 322 patients with non-ulcer dyspepsia, and 339 patients with peptic ulcer disease. Rapid urease test and Wright-Giemsa staining were used for diagnosis of H. pylori infection.RESULTS:
The prevalence of peptic ulcer disease in patients with cirrhosis was 24.3%. The prevalence of peptic ulcer disease in patients with cirrhosis divided into Child-Pugh classes A, B, and C was 22.3%, 21.0%, and 31.3%, respectively (p>0.05). The prevalence of H. pylori infection in the patients with cirrhosis, non-ulcer dyspepsia, and peptic ulcer without chronic liver disease were 35.1%, 62.4%, and 73.7%, respectively (p0.05). The prevalence of H. pylori infection in patients with hepatitis virus-related liver cirrhosis and in the patients with alcohol-related liver cirrhosis was 42.5% and 22.0%, respectively (p<0.001). The prevalence of H. pylori infection in patients with Child-Pugh classes A, B, and C liver cirrhosis was 51.5%, 30.5%, and 20.0%, respectively (p<0.001).CONCLUSIONS:
Factors other than H. pylori may be involved in the pathogenesis of peptic ulcer disease in the setting of liver cirrhosis.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Úlcera Gástrica
/
Índice de Gravidade de Doença
/
Prevalência
/
Helicobacter pylori
/
Infecções por Helicobacter
/
Cirrose Hepática
Tipo de estudo:
Estudo de prevalência
Limite:
Adulto
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
The Korean Journal of Internal Medicine
Ano de publicação:
2008
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS