Defibrotide Treatment for Hepatic Veno-occlusive Disease after Umbilical Cord Blood Transplantation / 대한소아혈액종양학회지
Korean Journal of Pediatric Hematology-Oncology
;
: 92-96, 2004.
Artigo
em Coreano
| WPRIM
| ID: wpr-114794
ABSTRACT
Veno-occlusive disease (VOD) of the liver is a life-threatening complication occurring early after blood or bone marrow transplantation (BMT). Effective treatment has not been established in case of severe forms of VOD. Defibrotide, a single-stranded polydeoxyribonucleotide, has been used on a compassionate basis in recent clinical trials with promising results. We report here with the first Korean experience of using defibrotide for the treatment of hepatic VOD occurring after unrelated umbilical cord blood transplant in a 2-year-old child with acute lymphoblastic leukemia. Defibrotide was administered for 23 days without any significant side effects with resolution of signs and symptoms of VOD.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Cordão Umbilical
/
Hepatopatia Veno-Oclusiva
/
Transplante de Medula Óssea
/
Empatia
/
Leucemia-Linfoma Linfoblástico de Células Precursoras
/
Sangue Fetal
/
Fígado
Limite:
Criança
/
Criança, pré-escolar
/
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Pediatric Hematology-Oncology
Ano de publicação:
2004
Tipo de documento:
Artigo
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