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Herpes Simplex Virus 2 Infection Rate and Necessity of Screening during Pregnancy: A Clinical and Seroepidemiologic Study
Yonsei Medical Journal ; : 401-407, 2012.
Artigo em Inglês | WPRIM | ID: wpr-114999
ABSTRACT

PURPOSE:

This study determined the seroprevalence of herpes virus 2 in gravidas and the differences between herpes virus 2-infected and healthy gravidas. The need to screen gravidas for herpes virus 2 was also evaluated. MATERIALS AND

METHODS:

A retrospective analysis involving 500 gravidas who underwent herpes virus 2 serologic testing and delivery in our hospital between January 2009 and August 2010 was performed. All patients in the study group were classified as herpes simplex virus 2 (HSV2) positive, and all cases were analyzed with respect to the clinical course of the pregnancy, pregnancy outcome, obstetric complications, and neonatal outcomes. SPSS software (version 14.0) was used for statistical analysis. A chi-square test and Student's t-test were used for statistical analysis.

RESULTS:

In the current study, the herpes virus 2 seroprevalence rate in gravidas was 17%. There was no significant difference in the rates of preterm delivery, premature rupture of membranes, preterm labor, and intrauterine growth restriction between the herpes virus 2-infected gravidas and the healthy control group. The rates of spontaneous abortion and sexually transmitted disease were higher in the herpes virus 2 infection group than the healthy control group.

CONCLUSION:

After educating gravidas on genital herpes and, if gravidas thereafter consent to herpes virus 2 screening, the risk of neonatal herpes virus 2 infections can be reduced. In addition, examination of gravidas for sexually transmitted diseases would increase as would appropriate treatment.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Complicações Infecciosas na Gravidez / Herpes Genital / Estudos Retrospectivos / Herpesvirus Humano 2 / Herpes Simples Tipo de estudo: Estudo diagnóstico / Estudo observacional / Estudo de rastreamento Limite: Adulto / Feminino / Humanos / Gravidez Idioma: Inglês Revista: Yonsei Medical Journal Ano de publicação: 2012 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Complicações Infecciosas na Gravidez / Herpes Genital / Estudos Retrospectivos / Herpesvirus Humano 2 / Herpes Simples Tipo de estudo: Estudo diagnóstico / Estudo observacional / Estudo de rastreamento Limite: Adulto / Feminino / Humanos / Gravidez Idioma: Inglês Revista: Yonsei Medical Journal Ano de publicação: 2012 Tipo de documento: Artigo