Early Recognition of Malignant Hyperthermia with Capnography: A case report / 대한마취과학회지
Korean Journal of Anesthesiology
;
: 667-672, 2002.
Artigo
em Coreano
| WPRIM
| ID: wpr-115504
ABSTRACT
Malignant hyperthemia is an autosomal-dominant inherited disorder of the skeletal muscle cell charac terized by a hypermetabolic response to all commonly used inhalational anesthetics and depolarizing muscle relaxants. The clinical syndrome includes muscle rigidity, hypercapnia, tachycardia and myoglobinuria as result of increased carbon dioxide production, oxygen consumption and muscle membrane breakdown. Early recognition and vigorous treatment are very important factors to determine patient's prognosis in malignant hyperthermia. However, it is very difficult to diagnose malignant hyperthermia during anesthesia because malignant hyperthermia presents with multiple nonspecific signs and laboratory findings of variable intensity and time course during and after exposure to anesthetic agents. We report a case of malignant hyperthermia which was diagnosed early using capnography before the appearance of hyperthermia and successfully treated. The malignant hyperthermia episode developed 20 minutes after induction of anesthesia with thiopental sodium, pancuronium, isoflurane, N2O and O2. When we suspected episode, we could not observe any classical signs of malignant hyperthermia except unexplained tachycardia and elevated end-tidal CO2. We discuss here the usefulness of capnography in early recognition of malignant hyperthermia and the importance of early recognition in prognosis.
Texto completo:
DisponíveL
Índice:
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Assunto principal:
Consumo de Oxigênio
/
Pancurônio
/
Prognóstico
/
Taquicardia
/
Tiopental
/
Dióxido de Carbono
/
Músculo Esquelético
/
Capnografia
/
Febre
/
Hipercapnia
Tipo de estudo:
Estudo prognóstico
Idioma:
Coreano
Revista:
Korean Journal of Anesthesiology
Ano de publicação:
2002
Tipo de documento:
Artigo
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