The Effect of beta-bocker on Postural Change of IOP

ABSTRACT

The intraocular pressures(IOP) were measured in both eyes of 30 healthy volunteers in sitting, supine, and 30 degrees head down positions One eye was pretreated with 1% carteolol or placebo(Tears naturale)applied in a masked, randomised fashion, while the other served as control. Although IOP changes in response to carteolol and to postural changes were significant(P<0.01), carteolol did not significantly alter relative changes in IOP from positional changes This results suggests that the overall pressure lowering effect may offer some protection to patients with glaucoma.