Sulfasalazine-induced Megaloblastic Anemia in Normal Serum Folate Level / 대한류마티스학회지
The Journal of the Korean Rheumatism Association
;
: 231-234, 2005.
Artigo
em Coreano
| WPRIM
| ID: wpr-117064
ABSTRACT
Sulfasalazine produces a varied spectrum of adverse reactions on the hematopoietic system. Sulfasalazine-induced megaloblastic anemia is very rare and a few cases have been reported in patients with inflammatory bowel disease. Most of them show a low serum folate level. The pathogenesis is known as folate deficiency by intestinal folate malabsorption, inhibition of folate enzyme, or hemolysis. We experienced a 43-year old female with Behcet's disease, who presented with megaloblastic anemia having normal serum folate level after treatement of sulfasalazine (2 g/day for 3 months). Megaloblastic anemia recovered after withdrawal of the drug only.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Sulfassalazina
/
Doenças Inflamatórias Intestinais
/
Ácido Fólico
/
Sistema Hematopoético
/
Hemólise
/
Anemia Megaloblástica
/
Megaloblastos
Limite:
Adulto
/
Feminino
/
Humanos
Idioma:
Coreano
Revista:
The Journal of the Korean Rheumatism Association
Ano de publicação:
2005
Tipo de documento:
Artigo
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