Retinoid Metabolism and Diabetes Mellitus
Diabetes & Metabolism Journal
;
: 167-180, 2012.
Artigo
em Inglês
| WPRIM
| ID: wpr-11718
ABSTRACT
Retinoid acid is a metabolite of vitamin A and functions as an important factor in cell survival, differentiation and death. Most previous studies on retinoid metabolism have focused on its association with cancer, hematologic and dermatologic disorders. Given the special concern over the recent increase in the prevalence of diabetes worldwide, the role of retinoid metabolism on glucose metabolism and insulin resistance in the human body is of marked importance. Therefore, in this issue, we review the literature on the association of retinoid metabolism with glucose tolerance, with regard to insulin secretion, pancreatic autoimmunity, insulin sensitivity and lipid metabolism. Further, we tried to assess the possibility of using retinoids as a novel therapeutic strategy for diabetes.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Retinoides
/
Vitamina A
/
Resistência à Insulina
/
Autoimunidade
/
Sobrevivência Celular
/
Prevalência
/
Corpo Humano
/
Diabetes Mellitus
/
Metabolismo dos Lipídeos
/
Glucose
Tipo de estudo:
Estudo de prevalência
Idioma:
Inglês
Revista:
Diabetes & Metabolism Journal
Ano de publicação:
2012
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS