Insulin Secretory Capacity and Insulin Resistance in Korean Type 2 Diabetes Mellitus Patients
Endocrinology and Metabolism
;
: 354-360, 2016.
Artigo
em Inglês
| WPRIM
| ID: wpr-117330
ABSTRACT
It is well known that many Korean patients with type 2 diabetes mellitus (T2DM) were non-obese and had decreased insulin secretion in past. However, during the past three decades, lifestyles in Korea have been westernized. As a result, the prevalence of obesity, the main cause of diabetes has increased. Thus, there is still a question as to whether the main pathophysiology of current Korean T2DM is insulin resistance or an insulin secretion defect. Because various anti-diabetes medications having different mechanisms of action are currently used as therapeutics, it is important to understand which of these factors is the main physiology in the development of diabetes in Koreans. In this review, we review changes in obesity prevalence, insulin resistance and insulin secretion defects in Korean T2DM during three decades.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fisiologia
/
Resistência à Insulina
/
Prevalência
/
Povo Asiático
/
Diabetes Mellitus Tipo 2
/
Insulina
/
Coreia (Geográfico)
/
Estilo de Vida
/
Obesidade
Tipo de estudo:
Estudo de prevalência
Limite:
Humanos
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Endocrinology and Metabolism
Ano de publicação:
2016
Tipo de documento:
Artigo
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