PKR as a Regulator of Inflammasome Activation
Journal of Bacteriology and Virology
;
: 145-147, 2013.
Artigo
em Inglês
| WPRIM
| ID: wpr-117656
ABSTRACT
Detection of pathogen by pattern recognition receptors leads to activation of inflammasome which plays a crucial role in immune system. The inflammasome regulates the release of cytokines, such as interleukin (IL)-1beta, IL-18 and high-mobility group box 1 (HMGB1). Double-stranded RNA-dependent protein kinase (PKR) is a critical component of an inflammatory complex. Recently, the critical role of PKR was reported in regulation of multiple inflammasomes.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Citocinas
/
Interleucinas
/
EIF-2 Quinase
/
Interleucina-18
/
Receptores de Reconhecimento de Padrão
/
Inflamassomos
/
Sistema Imunitário
Idioma:
Inglês
Revista:
Journal of Bacteriology and Virology
Ano de publicação:
2013
Tipo de documento:
Artigo
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