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Transfusion Premedication: A Single Center Study / 대한수혈학회지
Korean Journal of Blood Transfusion ; : 121-127, 2013.
Artigo em Coreano | WPRIM | ID: wpr-117797
ABSTRACT

BACKGROUND:

Acute transfusion reaction occurs during or within a few hours of transfusion with 0.5~3% of blood transfusion. Febrile non-hemolytic transfusion reactions (FNHTRs) and allergic transfusion reactions (ATRs) are the most common transfusion reactions. Premedication with acetaminophen and diphenhydramine has been used to prevent these reactions in 50~80% of transfusions. The purpose of this study was to describe the frequency of premedication and FNHTRs and ATRs according to premedication in Korea.

METHODS:

Between January 1 and 31, 2013, analysis of the first transfusion was performed retrospectively with chart review. A total of 549 cases were analyzed with regard to product of blood, care area, premedication, and FNHTRs and ATRs.

RESULTS:

Premedication was administered in 88.2% (484/549) of transfusions; 4 mg chlorphenamine, a well-known antihistamine, was used as premedication in all cases. Occurrence of FNHTRs was 7.7% without premedication and 3.7% with premedication. Occurrence of ATRs was 0% without premedication and 0.8% with premedication. The frequency of premedication was related to care area but not blood products.

CONCLUSION:

Premedication use was more frequent than previously reported. However, the sample size in this study is small; therefore, conduct of further prospective multicenter studies is needed.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Pré-Medicação / Incompatibilidade de Grupos Sanguíneos / Transfusão de Sangue / Clorfeniramina / Estudos Retrospectivos / Tamanho da Amostra / Difenidramina / Acetaminofen Tipo de estudo: Estudo observacional Idioma: Coreano Revista: Korean Journal of Blood Transfusion Ano de publicação: 2013 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Pré-Medicação / Incompatibilidade de Grupos Sanguíneos / Transfusão de Sangue / Clorfeniramina / Estudos Retrospectivos / Tamanho da Amostra / Difenidramina / Acetaminofen Tipo de estudo: Estudo observacional Idioma: Coreano Revista: Korean Journal of Blood Transfusion Ano de publicação: 2013 Tipo de documento: Artigo