Clinical Experience of 27 Pediatric Renal Transplantation at a Single Center / 대한비뇨기과학회지
Korean Journal of Urology
;
: 72-76, 2007.
Artigo
em Coreano
| WPRIM
| ID: wpr-119324
ABSTRACT
PURPOSE:
Renal transplantation is considered the treatment of choice for children with end-stage renal disease (ESRD). The results of renal transplantation were retrospectively analyzed to assess certain aspects of pediatric renal transplantation. MATERIALS ANDMETHODS:
Between January 1989 and January 2005, 27 pediatric kidney transplantations were carried out at our center. Fifteen (55.5%) patients underwent hemodialysis, two (7.4%) peritoneal dialysis and ten (37.0%) were conservative managed prior to treatment. Living- related donors provided 25 (92.6%) of the transplanted organs, with cadaver sources utilized for 2 (7.4%) patients. The donor age, organ source, etiology of ESRD, hospitalization period, postoperative complications, occurrence and number of acute rejections, and graft survival were assessed.RESULTS:
The causes of renal failure were chronic glomerulonephritis in 10 patients [IgA 3 nephropathy, 3 membranoproliferative glomerulonephritis (MPGN), 2 nephrotic syndrome and 2 focal segmental glomerulosclerosis (FSGS)], urinary tract anomalies in 6 (4 reflux nephropathy and 2 polycystic kidney), Alport syndrome in 1, hypertensive nephropathy in 2, systemic immunological disease in 1 and unknown causes in a further 5. Acute rejection occurred in 12 patients, all of who recovered after steroid pulse therapy. Growth and development failed in 2 patients. The postoperative complications included 4 urinary tract infections, 3 retroperitoneal hematomas, 2 lymphoceles and 1 acute ureteral obstruction. Four patients expired due to post-operative complications, such as disseminated intravascular coagulation (DIC), intracranial hematoma, sepsis and renal failure.CONCLUSIONS:
Pediatric renal transplantation can be successful, even in young children with ESRD.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Complicações Pós-Operatórias
/
Período Pós-Operatório
/
Doadores de Tecidos
/
Obstrução Ureteral
/
Sistema Urinário
/
Infecções Urinárias
/
Cadáver
/
Linfocele
/
Glomerulosclerose Segmentar e Focal
/
Glomerulonefrite Membranoproliferativa
Tipo de estudo:
Estudo observacional
Limite:
Criança
/
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Urology
Ano de publicação:
2007
Tipo de documento:
Artigo
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