Reduction of the Nailfold Capillary Blood Velocity in Cigarette Smokers / 가정의학회지
Korean Journal of Family Medicine
;
: 398-405, 2012.
Artigo
em Inglês
| WPRIM
| ID: wpr-11941
ABSTRACT
BACKGROUND:
Cigarette smoking causes cardiovascular disease and activates markers of endothelial dysfunction or injury. We investigated the nailfold capillary blood velocity (NCV) in cigarette smokers compared to non-smokers.METHODS:
Forty-eight men (eighteen non-smokers and thirty smokers) were recruited. We measured NCV using nailfold capillary microscopy and exhaled carbon monoxide (ECO) concentration three times (before smoking; NCV0min and ECO0min, and after smoking; NCV5min, ECO5min, NCV30min, and ECO30min), in a condition of fasting in the case of smokers. In non-smokers, the same measurements were taken without smoking. Additionally, personal cigarette smoking and alcohol drinking history were acquired by a self-administrated questionnaire.RESULTS:
Mean age, waist circumference, ECO0min, ECO5min, and ECO30min was higher and NCV5min and NCV30min were significantly lower in smokers compared to non-smokers. Total smoking years were negatively correlated with NCV5min. Average pack of the daily smoking, total pack-years, as well as total smoking years were also negatively correlated with NCV30min by regression analysis. After adjustment of significantly different variables, NCV30min was significantly lower in smokers. In the subgroup analysis, the interleukin-6 level was significantly increased in subjects with a long period of cigarette smoking compared with non-smokers.CONCLUSION:
Reduction of NCV in smokers is associated with personal smoking history, not with body composition or certain oxidative stress markers.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fumaça
/
Composição Corporal
/
Consumo de Bebidas Alcoólicas
/
Capilares
/
Monóxido de Carbono
/
Doenças Cardiovasculares
/
Fumar
/
Análise de Regressão
/
Jejum
/
Interleucina-6
Tipo de estudo:
Estudo diagnóstico
Limite:
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Korean Journal of Family Medicine
Ano de publicação:
2012
Tipo de documento:
Artigo
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