Blood Chimerism in a Dizygotic Dichorionic Pregnancy / 대한진단검사의학회지
The Korean Journal of Laboratory Medicine
;
: 521-524, 2010.
Artigo
em Inglês
| WPRIM
| ID: wpr-120810
ABSTRACT
Blood chimerism in twins is known to occur through the transfer of hematopoietic stem cells between the fetuses via a common placenta. We present a case of blood chimerism in a dizygotic dichorionic twin pregnancy. The female twin was delivered at 34 weeks of gestation, and the male twin was stillborn. Pathologic examination confirmed dichorionic diamniotic placentas. The karyotype of the female child was obtained using peripheral blood sample, and it revealed a mixture of 46,XX and 46,XY cells (chi 46,XY[13]/46,XX[7]). FISH analysis performed on the buccal cells by using CEP X/Y probe (Abbott Molecular Inc., USA) revealed 100% XX signals (nuc ish Xcen(DXZ1x2)[500]). Gross examination of the external genitalia and abdominal ultrasonography revealed no definitive abnormal findings in relation to sex differentiation. When XX/XY chimerism is present in blood lymphocytes, careful examination of external genitalia and reproductive organs and further studies are required to detect chimerism in non-hematopoetic tissues. This is a rare case of blood chimerism in dichorionic placentas, in contrast to those in monochorionic placentas.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Gêmeos Dizigóticos
/
Incompatibilidade de Grupos Sanguíneos
/
Fertilização in vitro
/
Ultrassonografia Pré-Natal
/
Idade Gestacional
/
Hibridização in Situ Fluorescente
/
Quimerismo
/
Doenças em Gêmeos
/
Cariotipagem
Tipo de estudo:
Estudo diagnóstico
Limite:
Adulto
/
Feminino
/
Humanos
/
Masculino
/
Recém-Nascido
/
Gravidez
Idioma:
Inglês
Revista:
The Korean Journal of Laboratory Medicine
Ano de publicação:
2010
Tipo de documento:
Artigo
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