A Case of Severe Chronic Active Epstein-Barr Virus Infection with T-cell lymphoproliferative Disorder
The Korean Journal of Internal Medicine
;
: 124-127, 2004.
Artigo
em Inglês
| WPRIM
| ID: wpr-122272
ABSTRACT
Chronic infection with Epstein-Barr virus (EBV) without previous immunodeficiency or immuno-suppressive therapy is relatively rare. Severe chronic active EBV (SCAEBV) infection was reported for the first time in 1984 as 'chronic mononucleosis syndrome', and diagnostic criteria were proposed. It is characterized by clinical features including fever, severe hepatosplenomegaly, lymphadenopathy, hematologic features such as anemia and thrombocytopenia, and elevated antibody titers to EBV. We experienced a 21-year-old woman who initially presented with fever and chronic fatigue; however, no definite diagnosis could be made at the time of admission. Three months after the initial admission, there was evidence of only splenomegaly and the patient had persistent, multiple, paraaortic lymphadenopathies in abdominal CT. Diagnostic splenectomy was performed, and SCAEBV infection with T-cell lymphoproliferative disorder was ultimately diagnosed.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Esplenectomia
/
Índice de Gravidade de Doença
/
Linfócitos T
/
Tomografia Computadorizada por Raios X
/
Doença Crônica
/
Infecções por Vírus Epstein-Barr
/
Diagnóstico Diferencial
/
Transtornos Linfoproliferativos
Tipo de estudo:
Estudo diagnóstico
Limite:
Adulto
/
Feminino
/
Humanos
Idioma:
Inglês
Revista:
The Korean Journal of Internal Medicine
Ano de publicação:
2004
Tipo de documento:
Artigo
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