Estimation of Paratuberculosis Prevalence in Dairy Cattle in a Province of Korea using an Enzyme-linked Immunosorbent Assay: Application of Bayesian Approach
Journal of Veterinary Science
;
: 51-56, 2003.
Artigo
em Inglês
| WPRIM
| ID: wpr-122778
ABSTRACT
To draw inferences about the sensitivity and specificity of the newly developed ELISA test for bovine paratuberculosis (PTB) diagnosis and posterior distribution on the prevalence of PTB in a province of Korea, we applied Bayesian approach with Gibbs sampler to the data extracted from the prevalence study in 1999. The data were from a single test results without a designated gold test. The prevalence estimates for PTB in study population ranged 3.2~5.3% for conservative and 6.7~7.1% for liberal, depending on the priors used. The simulated specificities of the ELISA close to one another, ranging 84.7~90.6%, whereas the sensitivity was somewhat spread out depending largely on the priors with a range of 46.4~88.2%. Our findings indicate that the ELISA method appeared useful as a screening tool at a minimum level in comparison to other diagnostic tests available for this disease in terms of sensitivity. However, this advantage comes at a cost of having low specificity of the test.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Paratuberculose
/
Ensaio de Imunoadsorção Enzimática
/
Doenças dos Bovinos
/
Prevalência
/
Teorema de Bayes
/
Coreia (Geográfico)
Tipo de estudo:
Estudo de prevalência
/
Estudo prognóstico
/
Fatores de risco
Limite:
Animais
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Journal of Veterinary Science
Ano de publicação:
2003
Tipo de documento:
Artigo
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