The Effect of Desmopressin in Neurogenic Bladder due to Spinal Cord in Jury / 대한비뇨기과학회지
Korean Journal of Urology
;
: 61-64, 1998.
Artigo
em Coreano
| WPRIM
| ID: wpr-124148
ABSTRACT
PURPOSE:
Nocturia and enuresis are common voiding problems in spinal cord injured patients despite a variety of management. The purpose of this study is to determine the efficacy of desmopressin, a synthetic analogue of antidiuretic mono, as an alternative treatment in the management of spinal cord injured(SCI) patients with neurogenic bladder dysfunction unresponsive to conventional therapy. MATERIALS ANDMETHODS:
Fourteen SCI patients with nocturia or enuresis were included in this study. The patients received 10microgram desmopressin intranasally at bedtime once every 24 hours.RESULTS:
There was a significant decrease in nocturnal urinary volume, frequency of nocturia and nocturnal enuresis during nighttime after desmopressin administration. Two patients stopped desmopressin because of side effects. 8 of 12 patients improved with desmopressin and the remainder had no effect. There was no serum abnormality, although there were side effects in three cases, such as gastro-intestinal trouble, chest discomfort or nasal congestion.CONCLUSIONS:
Desmopressin is safe and effective in the management of nocturia or enuresis due to neurogenic bladder dysfunction in selected SCI patients.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Medula Espinal
/
Traumatismos da Medula Espinal
/
Tórax
/
Bexiga Urinaria Neurogênica
/
Estrogênios Conjugados (USP)
/
Desamino Arginina Vasopressina
/
Enurese
/
Enurese Noturna
/
Noctúria
Limite:
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Urology
Ano de publicação:
1998
Tipo de documento:
Artigo
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