The effect of body mass index of on the outcome of in vitro fertilization and embryo transfer in patients with polycystic ovary syndrome / 대한산부인과학회지
Korean Journal of Obstetrics and Gynecology
; : 75-82, 2009.
Article
em Ko
| WPRIM
| ID: wpr-124408
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVE: This study was performed to evaluate the effect of body mass index (BMI) on the outcome of in vitro fertilization and embryo transfer (IVF-ET) in patients with polycystic ovary syndrome (PCOS). METHODS: Ninety-six patients with PCOS who completed their first cycle of IVF-ET were included in this retrospective study. All patients were stimulated by GnRH antagonist multi-dose protocol. The patients were divided into one of two groups on the basis of BMI > or =23 kg/m2 vs. BMI or =23kg/m2 were divided into patient group with 23 or =25 kg/m2, and these three groups were also compared in regard to the outcome of IVF-ET. RESULTS: The total amount and duration of rhFSH administration were significantly higher in PCOS women with BMI > or =23 kg/m2 than in those with BMI or =23 kg/m2 (17.4% vs 7.8%, P=0.024). When compared three group divided on the basis of BMI or =25 kg/m2, similar results were showed in women with BMI > or =25 kg/m2, although implantation rate in women with BMI > or =25 kg/m2 was lower with borderline significance (P=0.069). CONCLUSION: Obesity (BMI > or =23 kg/m2) has a detrimental effect on implantation rate and is associated with the increased total amount and duration of rhFSH administration for ovarian stimulation in IVF-ET cycle. Consequently BMI may be a predictor for IVF outcomes in patients with PCOS.
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Índice:
WPRIM
Assunto principal:
Indução da Ovulação
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Síndrome do Ovário Policístico
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Fertilização in vitro
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Índice de Massa Corporal
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Estudos Retrospectivos
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Hormônio Liberador de Gonadotropina
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Transferência Embrionária
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Estruturas Embrionárias
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Obesidade
Tipo de estudo:
Observational_studies
/
Prognostic_studies
Limite:
Female
/
Humans
Idioma:
Ko
Revista:
Korean Journal of Obstetrics and Gynecology
Ano de publicação:
2009
Tipo de documento:
Article