Multiple Lymphomatous Polyposis of the Gastrointestinal Tract: Report of Three Cases

ABSTRACT

In 1961, Cornes first introduced the term multiple lymphomatous polyposis(MLP), and since then, this very raredisease has been considered as a malignant lymphoma originating in the mantle zone of gastrointestinal lymphoidtissue. MLP presents with a 0.5-2.0cm sized polypoid tumor, which affects long segments of the alimentary tractand frequently invades the mesenteric lymph nodes. It often consists of a dominant mass rather than polyps. Wedescribe three cases of endoscopically proven multiple lymphomatous polyposis, and include a review of theliterature. In differentiating multiple lymphomatous polyposis and other types of multiple polyposis in thegastrointestinal tract, the following features are helpful the smooth surface of polyps, which is similar to agem seen during a barium examination ; the typical appearance of a gastric submucosal tumor and hypertrophiedgastric mucosal folds in UGI; the presence of enlarged lymph nodes, as seen on abdominal CT scanning.