Neurologic Complications after Hematopoietic Stem Cell Transplantation in Children / 소아과
Korean Journal of Pediatrics
;
: 978-985, 2004.
Artigo
em Coreano
| WPRIM
| ID: wpr-124567
ABSTRACT
PURPOSE:
Neurologic complications(NC) after hematopoietic stem cell transplantation(HSCT) are important because of high mortality and severe sequelae. We analyzed the incidence, manifestation and risk factors of NC in 61 children undergoing HSCT.METHODS:
We retrospectively analyzed NC in 61 cases(42 male and 19 female, aged one to 16 years) given HSCT between 1996 and 2003 due to hematologic malignacies, solid tumors, or other hematologic diseases.RESULTS:
NC were seen in 22 children(36.0%). Herpes zoster was the most frequent one(n=17, 27.9 %), followed by seizure(n=8, 13.1%), CNS infection(n=3, 4.9%), cyclosporin toxicity(n=3, 4.9%), CVA (n=2, 3.3%), and chemotherapy injury(n=1, 1.6%). Among the 22 cases, 12 developed herpes zoster only and 10 developed other NC in addition to herpes zoster. Two patients died of NC. The incidence of NC was not affected by various factors, including type and source of HSCT or previous cranial radiation.CONCLUSION:
NC were frequent in children who underwent HSCT. We should acknowlege the occurrence of various NC after HSCT. Further study is needed to develop measures to minimize these complications.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Incidência
/
Fatores de Risco
/
Mortalidade
Tipo de estudo:
Estudo de etiologia
/
Estudo de incidência
/
Estudo prognóstico
/
Fatores de risco
Limite:
Criança
/
Feminino
/
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Korean Journal of Pediatrics
Ano de publicação:
2004
Tipo de documento:
Artigo
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