Diagnostic Value of Preoperative Serum Thyroglobulin Measurement for the Diagnosis of Malignancy in Follicular or Hurthle Cell Neoplasms of the Thyroid Gland / 고신대학교의과대학학술지
Kosin Medical Journal
;
: 17-22, 2014.
Artigo
em Coreano
| WPRIM
| ID: wpr-124658
ABSTRACT
OBJECTIVES:
The aim of this retrospective study was whether serum Tg predicts malignancy in follicular or Hurthle-cell neoplasms on fine needle aspiration.METHODS:
A chart review of 111 patients (90 females, 21 males; mean age 46.8 +/- 11.9 years) with follicular or Hurthle-cell neoplasms on fine needle aspiration, who were surgically treated between Sep. 2001 and Sep. 2011, was performed. Predictive factors for malignancy were identified by the chi-squared test and multivariate logistic regression.RESULTS:
There were no differences between 41 malignant and 70 benign lesions in serum Tg or any of the normalized indexes. Receiver-operator characteristic analysis revealed no cut-off value. Lesions with serum Tg levels greater than 500 g/L had no significant difference. And also there were no independent predictors of malignancy by multivariate logistic regression.CONCLUSIONS:
In this study, the author found that serum Tg has poor accuracy for predicting malignancy in follicular or Hurthle cell neoplasms on fine needle aspiration.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Tireoglobulina
/
Glândula Tireoide
/
Neoplasias da Glândula Tireoide
/
Modelos Logísticos
/
Estudos Retrospectivos
/
Biópsia por Agulha Fina
/
Diagnóstico
Tipo de estudo:
Estudo diagnóstico
/
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Kosin Medical Journal
Ano de publicação:
2014
Tipo de documento:
Artigo
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