Effects of alfaxalone on echocardiographic examination in healthy dogs / 대한수의학회지
Korean Journal of Veterinary Research
;
: 221-225, 2015.
Artigo
em Inglês
| WPRIM
| ID: wpr-125573
ABSTRACT
This study evaluated the effects of alfaxalone (3 mg/kg, intravenously) on echocardiographic examination in healthy dogs using echocardiography. Six adult Beagle dogs were used for this study. Left ventricular dimensions with systolic indexes, trans-blood flow at all cardiac valvular annulus and trans-mitral tissue Doppler values were measured from routine transthoracic echocardiography. Although the changes were not statistically significant, heart rate, left ventricular end-systolic diameter, left ventricular end-diastolic diameter, peak velocities of tricuspid A-wave and transpulmonic flow were increased after alfaxalone induction, while systolic blood pressure, fractional shortening, left ventricular ejection fraction, peak velocities of mitral E-wave, mitral A wave, tricuspid E-wave, transaortic flow and medial e'-, a'- and s'-peaks decreased after alfaxalone induction. No dogs showed hypoxemia during sedation, regardless of intubation and oxygen supply. Although alfaxalone showed mild cardiovascular depression, this protocol could be a good alternative sedative protocol for echocardiographic examination in healthy dogs because the cardiovascular depression was statistically and clinically insignificant. However, further studies in dogs with heart diseases should be conducted to confirm these findings after alfaxalone induction.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Oxigênio
/
Volume Sistólico
/
Pressão Sanguínea
/
Ecocardiografia
/
Depressão
/
Cardiopatias
/
Frequência Cardíaca
/
Ventrículos do Coração
/
Intubação
/
Hipóxia
Tipo de estudo:
Guia de Prática Clínica
Limite:
Animais
/
Humanos
Idioma:
Inglês
Revista:
Korean Journal of Veterinary Research
Ano de publicação:
2015
Tipo de documento:
Artigo
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