A Case of Idiopathic Myelofibrosis Causing an Esophageal Variceal Hemorrhage / 대한소화기내시경학회지
Korean Journal of Gastrointestinal Endoscopy
;
: 549-553, 2000.
Artigo
em Coreano
| WPRIM
| ID: wpr-125815
ABSTRACT
Idiopathic Myelofibrosis (IMF), a clonal disorder of a multipotent hemtopoietic progenitor cell of unknown etiology, is characterized by massive splenomegaly, leukoerythroblastic blood changes, and bone marrow fibrosis. Portal hypertension occurs in approximately 10% of patients with IMF. Alsom there mey be bleeding from esophageal varices. A 59-year-old woman was admitted with intermittent abdominal distension and melena. An esophagogastroduodenoscopy revealed extensive esophageal varices with red colored signs, and subsequently esophageal variceal ligation was performed. Marked splenomegaly and ascites was observed through abdominal US and MRI scan. Bone marrow biopsy revealed an increase in reticulin and fibrosis. Extramedullary hematopoiesis and sinusoidal change were observed in the liver biopsy specimen. This case of IMF causing an esophageal variceal hemorrhage is herein reported.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Ascite
/
Reticulina
/
Esplenomegalia
/
Células-Tronco
/
Biópsia
/
Medula Óssea
/
Fibrose
/
Hematopoese Extramedular
/
Imageamento por Ressonância Magnética
/
Varizes Esofágicas e Gástricas
Limite:
Feminino
/
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Gastrointestinal Endoscopy
Ano de publicação:
2000
Tipo de documento:
Artigo
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