HLA Antigens, T and B Lymphocytes and other Associated Laboratory Findings in Patients with Vitiligo / 대한피부과학회지
Korean Journal of Dermatology
;
: 461-466, 1984.
Artigo
em Coreano
| WPRIM
| ID: wpr-125882
ABSTRACT
Although vitiligo is a common disorder with well-known clinical features, its etiology is still vague. It has been suggested that immunologic factors are important in the pathophysiology of vitiligo. And the association of HLA antigens with vitiligo has been reported. Authors examined HLA phenotypes in thirty-nine patients, T lymphocytes in thirty- three patients, B lymphocytes in thirty-one patients, and quantitation of IgG, IgA, IgM and IEP(immunoelectrophoresis) in twenty-five patients with vitiligo in this study. T3 and T4 were investigated in twelve patients, CBC in thirty-nine and urinalysis in thirty-five patients with vitiligo for screening of associated diseases ; thyroid disease, anemia and diabetes mellitus. The results are as follows; The frequency of HLA A9, Bw15 and Bw22 was significantly decreased in vitiligo patients compared to control group(p=0. 003, 0. 02, 0. OR) 2. There were no significant differences in the results of total and active lymphocytes and B lymphocytes in vitiligo patients compared to the control group. The results of quantitation of IgG, IgA, IgM and IEP showed within normal lirnits except one, an increased IgG, 2,200rng/100ml (normal 500 1,500) and polyclonal gammopathy. 4. Among twelve vitiligo patients, one showed increased TR, 355ng/100ml (normal 80 220) and T4, 17. 3pg/100ml (normal 5 13). 5. CBC and urinalysis were within normal limits in all patients.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fenótipo
/
Doenças da Glândula Tireoide
/
Vitiligo
/
Imunoglobulina A
/
Imunoglobulina G
/
Imunoglobulina M
/
Linfócitos B
/
Linfócitos
/
Linfócitos T
/
Programas de Rastreamento
Tipo de estudo:
Estudo diagnóstico
/
Estudo prognóstico
/
Estudo de rastreamento
Limite:
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Dermatology
Ano de publicação:
1984
Tipo de documento:
Artigo
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