The impact of high-flux dialysis on mortality rates in incident and prevalent hemodialysis patients
The Korean Journal of Internal Medicine
;
: 774-784, 2014.
Artigo
em Inglês
| WPRIM
| ID: wpr-126098
ABSTRACT
BACKGROUND/AIMS:
The effect of high-flux (HF) dialysis on mortality rates could vary with the duration of dialysis. We evaluated the effects of HF dialysis on mortality rates in incident and prevalent hemodialysis (HD) patients.METHODS:
Incident and prevalent HD patients were selected from the Clinical Research Center registry for end-stage renal disease (ESRD), a Korean prospective observational cohort study. Incident HD patients were defined as newly diagnosed ESRD patients initiating HD. Prevalent HD patients were defined as patients who had been receiving HD for > 3 months. The primary outcome measure was all-cause mortality.RESULTS:
This study included 1,165 incident and 1,641 prevalent HD patients. Following a median 24 months of follow-up, the mortality rates of the HF and low-flux (LF) groups did not significantly differ in the incident patients (hazard ratio [HR], 1.046; 95% confidence interval [CI], 0.592 to 1.847; p = 0.878). In the prevalent patients, HF dialysis was associated with decreased mortality compared with LF dialysis (HR, 0.606; 95% CI, 0.416 to 0.885; p = 0.009).CONCLUSIONS:
HF dialysis was associated with a decreased mortality rate in prevalent HD patients, but not in incident HD patients.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fatores de Tempo
/
Distribuição de Qui-Quadrado
/
Modelos de Riscos Proporcionais
/
Sistema de Registros
/
Incidência
/
Prevalência
/
Análise Multivariada
/
Estudos Prospectivos
/
Fatores de Risco
/
Diálise Renal
Tipo de estudo:
Estudo de etiologia
/
Estudo de incidência
/
Estudo observacional
/
Estudo de prevalência
/
Estudo prognóstico
/
Fatores de risco
Limite:
Idoso
/
Feminino
/
Humanos
/
Masculino
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
The Korean Journal of Internal Medicine
Ano de publicação:
2014
Tipo de documento:
Artigo
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