The Combined Peripheral and Central Demyelinating Disease Associated with Pulmonary Tuberculosis

ABSTRACT

Although there are some reports of neuromyelitis optica or Guillain-Barre syndrome in patients with tuberculosis, the combined peripheral and central demyelination associated with tuberculosis has not yet been reported. We report a 43 year-old man with active pulmonary tuberculosis presenting with Guillain-Barre syndrome, bilateral optic neuritis, and multiple central nervous system white matter lesions on MRI. Our case suggests that tuberculosis may be associated with the combined peripheral and central demyelination.