Comparison of clinical usefulness of low-calorie-diet combined with exercise and low-calorie-diet alone

ABSTRACT

BACKGROUND: To assess the efficacy and safety of low-calorie-diet(LCD) using formular diet and to compare clinical usefulness of LCD combined with exercise with LCD alone, sixty obese females were prescribed LCD with exercise or LCD alone, randomly. METHODS: Thirty obese females were treated with LCD of 1,000kcal/d for 8 weeks(group A). Another thirty obese females were treated with LCD of 1,000kcal/d combined with supervised aerobic exercise for 8 weeks(group B). RESULTS: 22 out of 30 obese females in group A[37.3+/-5.0yr ; body fat 40.3+/-3.9%] and 26 out of 30 obese females in group B[37.9+/-7.6yr ; body fat 41.5+/-3.7%] completed the study. At the eighth week, mean weight loss was 5.8+/-2.1kg(8.1%) for group A, and 6.8+/-1.6kg(9.7%) for group B. Differences in weight loss between two groups were statistically significant(p<0.05). In group 4 blood pressure, serum glucose, uric acid, total cholesterol, HDL-cholesterol, sodium, chloride, body fat were significantly reduced, and serum zinc, calcium, phosphorus were significantly increased(p<0.05). In group B, blood pressure, serum glucose, uric acid, total cholesterol, HDL-cholesterol, triglyceride, insulin, iron, sodium, body fat were significantly reduced, and serum zinc, calcium, phosphorus, magnesium were significantly increased(p<0.05). However, the differences of the changes in the above laboratory data between two groups were not statistically significant. Side effects were few and occurred mainly during the first week of the trial. CONCLUSIONS: Low calorie diet for 8 weeks decreased body fat, BP, glucose, uric acid, total cholesterol, MDL-cholesterol levels significantly, and when combined with exercise weight loss was much more than LCD only.