Liver dysfunction induced by systemic hypersensitivity reaction to lamotrigine: case report
Clinical and Molecular Hepatology
;
: 180-182, 2015.
Artigo
em Inglês
| WPRIM
| ID: wpr-128613
ABSTRACT
Lamotrigine is an anticonvulsant drug used to treat partial and generalized seizure disorders. Hypersensitivity to lamotrigine usually causes mild symptoms such as fever, rash, and slight invasion of internal organs. However, a 33-year-old male patient who was admitted with Stevens-Johnson syndrome after taking lamotrigine for 15 days experienced hepatic failure and died 5 days after admission. This case demonstrates the importance of realizing that lamotrigine can lead to fatal hepatic failure, and that tests for the normal liver function should be performed when administering lamotrigine.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Aspartato Aminotransferases
/
Triazinas
/
Síndrome de Stevens-Johnson
/
Falência Hepática
/
Alanina Transaminase
/
Hipersensibilidade a Drogas
/
Fígado
/
Anticonvulsivantes
Limite:
Adulto
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Clinical and Molecular Hepatology
Ano de publicação:
2015
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS