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Hepatic and Small Bowel Mucormycosis after Chemotherapy in a Patient with Acute Myeloid Leukemia: A Case Report and Literature Review / 감염과화학요법
Infection and Chemotherapy ; : 516-521, 2012.
Artigo em Coreano | WPRIM | ID: wpr-130653
ABSTRACT
We present a case of a 64-year-old woman with acute myeloid leukemia who developed a hepatic abscess during the neutropenic period after induction chemotherapy. To treat the abscess, meropenem and ciprofloxacin were administered to target Klebsiella pneumoniae and percutaneous drainage performed. As a result, the patient's fever and c-reactive protein (CRP) subsequently improved. After six weeks of antibiotic therapy, an abdominal computed tomography scan revealed remains of the liver abscess as well as an ileus in the small bowel. Molds from the Mucor genus were cultured from repeated liver abscess drainage and an abscess wall biopsy confirmed hepatic mucormycosis. Along with administration of amphotericin-B deoxycholate for four weeks, we performed lobectomy for hepatic mucormycosis and small bowel resection for a suspected small bowel mucormycosis. After these operations, the patient received liposomal amphotericin B for three weeks and was then maintained with oral posaconazole for more than four weeks. Our case report suggests that hepatic mucormycosis should be considered when a hepatic abscess exhibits a retarded response to antibacterial agents, especially for patients with risk factors. In addition, because an isolated hepatic mucormycosis is infrequent, a thorough search for the extent of the disease is necessary before surgical resection.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Triazóis / Biópsia / Proteína C-Reativa / Leucemia Mieloide Aguda / Ciprofloxacina / Tienamicinas / Anfotericina B / Drenagem / Fatores de Risco / Íleus Tipo de estudo: Estudo de etiologia / Fatores de risco Limite: Feminino / Humanos Idioma: Coreano Revista: Infection and Chemotherapy Ano de publicação: 2012 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Triazóis / Biópsia / Proteína C-Reativa / Leucemia Mieloide Aguda / Ciprofloxacina / Tienamicinas / Anfotericina B / Drenagem / Fatores de Risco / Íleus Tipo de estudo: Estudo de etiologia / Fatores de risco Limite: Feminino / Humanos Idioma: Coreano Revista: Infection and Chemotherapy Ano de publicação: 2012 Tipo de documento: Artigo