A case of Creutzfeldt-Jakob disease in a patient on hemodialysis
Kidney Research and Clinical Practice
;
: 76-78, 2012.
Artigo
em Inglês
| WPRIM
| ID: wpr-13103
ABSTRACT
We report an unusual case of probable Creutzfeldt-Jakob disease (CJD) in hemodialysis patient. A woman 59 years of age with a past history of hypertension and end-stage renal disease presented with a stuporous state preceded by rapidly progressive cognitive dysfunction, myoclonus, and akinetic mutism. At first, the cause of the altered mental status was assumed to be uremic or hypertensive encephalopathy combined with fever. Proper managements, however, did not improve the neurologic symptoms. Diffusion-weighted magnetic resonance imaging revealed bilaterally asymmetric high signal intensity in both basal ganglia and cerebral cortices. Electroencephalography showed diffuse generalized theta-to-delta range slow wave and intermittent medium-to-high voltage complexes with a characteristic triphasic pattern on both hemispheres. Cerebrospinal fluid assay for the 14-3-3 protein was positive and diagnostic of CJD.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Gânglios da Base
/
Imageamento por Ressonância Magnética
/
Córtex Cerebral
/
Síndrome de Creutzfeldt-Jakob
/
Diálise Renal
/
Encefalopatia Hipertensiva
/
Proteínas 14-3-3
/
Diálise
/
Afasia Acinética
/
Eletroencefalografia
Limite:
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Kidney Research and Clinical Practice
Ano de publicação:
2012
Tipo de documento:
Artigo
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