Safety and Tolerability of OROS Methylphenidate for the Treatment of ADHD
Journal of the Korean Academy of Child and Adolescent Psychiatry
;
: S24-S45, 2012.
Artigo
em Coreano
| WPRIM
| ID: wpr-131086
ABSTRACT
We review the effect of methylphenidate, focusing on Osmotic-controlled Release Oral delivery System (OROS) methylphenidate, on cardiovascular system, appetite and growth, sleep, tic, epilepsy, psychiatric and rare adverse events. Although OROS methylphenidate has side effects including increased heart rate or blood pressure, decreased appetite, delayed sleep onset, emergence or aggravation of tics, withdrawal or changes in mood, these effects appeared to be minimal in impact or difficult to distinguish from risk to untreated population and tended to be improved by dose adjustment or drug discontinuation. However, in subjects with underlying cardiac problems, uncontrolled epilepsy, previous psychotic episode, clinicians should pay attention and balance the risk and benefit.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Apetite
/
Pressão Sanguínea
/
Sistema Cardiovascular
/
Tiques
/
Epilepsia
/
Frequência Cardíaca
/
Metilfenidato
Idioma:
Coreano
Revista:
Journal of the Korean Academy of Child and Adolescent Psychiatry
Ano de publicação:
2012
Tipo de documento:
Artigo
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