The Effect of Ocufen(R) Eyedrops on Mydriagis during Cataract Surgery

ABSTRACT

We studied the effect of Ocufen(R), a new ophthalmic nonsteroidal antiinflammatory agent(Flubiprofen), on reducing pupillary constiction during cataract surgery. The study was performed on 63 patients(experimental group43 patients control group20 patients). Pupil diameters were meagured at the beginning, after anterior capsulotonly, after lens cortex extraction and after IOL insertion. Pre-operative pupillary diameters were not statisitically different between the control and experimental groups. The change of the pupillary deiameter from the beginning to after IOL insertion averaged 1.0mm in experimental group and 1.9mm in control group. The difference between two groups was statistically significant(P<0.01). The experimental group maintained pupillary dilation better on the average and much smaller incidence of pupil constriction greater than 2mm.