Generalized Dowling-Degos Disease: Case Reports
Annals of Dermatology
;
: 360-364, 2013.
Artigo
em Inglês
| WPRIM
| ID: wpr-131864
ABSTRACT
Dowling-Degos disease (DDD) is a rare autosomal dominant trait characterized by numerous, symmetrical, progressive and pigmented macules over the axillae, groins, face, neck, arms and trunk as well as scattered comedo-like lesions (dark dot, follicles) and pitted acneiform scars. Histopathology is diagnostic testing using a distinctive form of acanthosis, characterized by an irregular elongation of thin branching rete ridges, with a concentration of melanin at the tips. We report cases of generalized DDD in a single family with autosomal dominant penetrance. DDD can be presented in a generalized form with hypopigmented lesions instead of reticulate hyperpigmentation confined to the flexor areas. This form can be differentiated from DUH by histopathology.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Braço
/
Dermatopatias Genéticas
/
Axila
/
Cicatriz
/
Dermatopatias Papuloescamosas
/
Hiperpigmentação
/
Penetrância
/
Diclorodifenildicloroetano
/
Testes Diagnósticos de Rotina
/
Virilha
Limite:
Humanos
Idioma:
Inglês
Revista:
Annals of Dermatology
Ano de publicação:
2013
Tipo de documento:
Artigo
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