Association Study of the Relationship between Endometriosis and Polymorphism of p53 Codon 72 / 대한불임학회지
Korean Journal of Fertility and Sterility
;
: 311-316, 2002.
Artigo
em Coreano
| WPRIM
| ID: wpr-131935
ABSTRACT
OBJECTIVE:
The present study was performed to evaluate the association of p53 codon 72 polymorphism and endometriosis. MATERIALS ANDMETHODS:
We investigate 74 women who were operated for endometriosis and 93 women who had no endometriotic lesion proved by operation. Polymerase chain reaction was used to detect p53 codon polymorphisms.Result:
We have found no significant difference between endometriosis and control group in the p53 codon polymorphism. The respective proportion of arginine homozygotes, heterozygotes and proline homozygotes in endometriosis group were 18.9%, 62.2% and 18.9%, respectively, and were 12.9%, 75.2% and 11.9%, respective in the group without endometriosis.CONCLUSION:
Endometriosis is not associated with p53 polymorphism in Korean endometriosis patients.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Arginina
/
Códon
/
Prolina
/
Reação em Cadeia da Polimerase
/
Endometriose
/
Heterozigoto
/
Homozigoto
Limite:
Feminino
/
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Fertility and Sterility
Ano de publicação:
2002
Tipo de documento:
Artigo
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