Successful Pamidronate Treatment of Osteogenesis Imperfecta Type III Infant with Multiple Fractures
Annals of Pediatric Endocrinology & Metabolism
;
: 194-197, 2012.
Artigo
em Inglês
| WPRIM
| ID: wpr-132351
ABSTRACT
Osteogenesis imperfect (OI) is a generalized connective tissue disorder. We report the female neonate case with OI type III who showed severe bone deformities and fractures in utero. At birth, she showed multiple fractures in the clavicle, rib, femur, and wormian bone in the skull X-ray. We initiated pamidronate disodium infusion 30 mg/m2 in cycles of 3 consecutive days from when she was 4 days old, monthly for the first 3 months and every 2 months thereafter without adverse effects.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Osteogênese
/
Osteogênese Imperfeita
/
Costelas
/
Crânio
/
Anormalidades Congênitas
/
Densidade Óssea
/
Clavícula
/
Tecido Conjuntivo
/
Parto
/
Difosfonatos
Limite:
Feminino
/
Humanos
/
Lactente
/
Recém-Nascido
Idioma:
Inglês
Revista:
Annals of Pediatric Endocrinology & Metabolism
Ano de publicação:
2012
Tipo de documento:
Artigo
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