Massive pulmonary hemorrhage in enterovirus 71-infected hand, foot, and mouth disease / 소아과
Korean Journal of Pediatrics
;
: 112-115, 2015.
Artigo
em Inglês
| WPRIM
| ID: wpr-133204
ABSTRACT
Hand, foot, and mouth disease (HFMD) is an acute, mostly self-limiting infection. Patients usually recover without any sequelae. However, a few cases are life threatening, especially those caused by enterovirus 71 (EV71). A 12-month-old boy was admitted to a primary hospital with high fever and vesicular lesions of the mouth, hands, and feet. After 3 days, he experienced 3 seizure episodes and was referred to our hospital. On admission, he was conscious and his chest radiograph was normal. However, 6 hours later, he suddenly lost consciousness and had developed a massive pulmonary hemorrhage that continued until his death. He experienced several more intermittent seizures, and diffuse infiltration of both lung fields was observed on chest radiography. Intravenous immunoglobulin, dexamethasone, cefotaxime, leukocyte-depleted red blood cells, fresh frozen plasma, inotropics, vitamin K, and endotracheal epinephrine were administered. The patient died 9 hours after intubation, within 3 days from fever onset. EV71 subgenotype C4a was isolated retrospectively from serum and nasopharyngeal swab by real-time reverse transcription-polymerase chain reaction. Here, we report a fatal case of EV71-associated HFMD with sudden-onset massive pulmonary hemorrhage and suspected encephalitis.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Plasma
/
Convulsões
/
Tórax
/
Vitamina K
/
Imunoglobulinas
/
Dexametasona
/
Radiografia
/
Radiografia Torácica
/
Epinefrina
/
Cefotaxima
Tipo de estudo:
Estudo diagnóstico
/
Estudo observacional
Limite:
Humanos
/
Lactente
/
Masculino
Idioma:
Inglês
Revista:
Korean Journal of Pediatrics
Ano de publicação:
2015
Tipo de documento:
Artigo
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