Increased survival in hepatitis c patients who underwent living donor liver transplant: a case-control study with propensity score matching
Annals of Surgical Treatment and Research
;
: 293-299, 2017.
Artigo
em Inglês
| WPRIM
| ID: wpr-134101
ABSTRACT
PURPOSE:
There is no consensus regarding the difference in outcomes of HCV in patients who receive living donor liver transplantation (LDLT) or compared to deceased donor liver transplantation (DDLT). The aims of this study were to compare characteristics between LDLT and DDLT groups and to identify risk factors affecting patient survival.METHODS:
We retrospectively reviewed the multicenter records of 192 HCV RNA-positive patients who underwent liver transplantation.RESULTS:
Thirty-five patients underwent DDLT, and 146 underwent LDLT. The 1-, 3-, and 5-year patient survival rates were 66.7%, 63.0%, and 63.0% in the DDLT group and 86.1%, 82.3%, and 79.5% in the LDLT group (P = 0.024), respectively. After propensity matching, the patient survival curve of the LDLT group was higher than that of the DDLT group. However, there was no statistically significant difference in patient survival between the 2 groups (P = 0.061). Recipient age ≥ 60 years, LDLT, and use of tacrolimus were positively associated with patient survival in multivariate analyses.CONCLUSION:
LDLT appears to be suitable for HCV-infected patients if appropriate living donor is available.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Doadores de Tecidos
/
Estudos de Casos e Controles
/
Análise Multivariada
/
Taxa de Sobrevida
/
Estudos Retrospectivos
/
Fatores de Risco
/
Terapia de Imunossupressão
/
Transplante de Fígado
/
Tacrolimo
/
Hepatite C
Tipo de estudo:
Estudo de etiologia
/
Guia de Prática Clínica
/
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Limite:
Humanos
Idioma:
Inglês
Revista:
Annals of Surgical Treatment and Research
Ano de publicação:
2017
Tipo de documento:
Artigo
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