Five Computer Simulation Studies of Whole-Genome Fragment Assembly: The Case of Assembling Zymomonas mobilis ZM4 Sequences
Genomics & Informatics
;
: 183-190, 2004.
Artigo
em Inglês
| WPRIM
| ID: wpr-13644
ABSTRACT
An approach for genome analysis based on assembly of fragments of DNA from the whole genome can be applied to obtain the complete nucleotide sequence of the genome of Zymomonas mobilis. However, the problem of fragment assembly raise thorny computational issues. Computer simulation studies of sequence assembly usually show some abnormal assemblage of artificial sequences containing repetitive or duplicated regions, and suggest methods to correct those abnormalities. In this paper, we describe five simulation studies which had been performed previous to the actual genome assembly process of Zymomonas mobilis ZM4.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Simulação por Computador
/
DNA
/
Sequência de Bases
/
Genoma
/
Zymomonas
Idioma:
Inglês
Revista:
Genomics & Informatics
Ano de publicação:
2004
Tipo de documento:
Artigo
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