Effect of Levothyroxine Treatment on Clinical Symptoms in Hypothyroid Patients with Chronic Urticaria and Thyroid Autoimmunity
Annals of Dermatology
;
: 199-204, 2016.
Artigo
em Inglês
| WPRIM
| ID: wpr-136936
ABSTRACT
BACKGROUND:
Thyroid autoimmunity has been increasingly reported to be associated with chronic urticaria (CU), and the possible clinical benefit of thyroid hormone or anti-thyroid drugs in some CU patients with autoimmune thyroid disease has been studied. However, the effect of thyroid hormone or anti-thyroid drugs on clinical symptoms of CU remains unclear.OBJECTIVE:
We investigated the clinical response of urticaria to the treatment of thyroid dysfunction.METHODS:
Medical records of patients with CU evaluated for thyroid autoimmunity and thyroid function were collected and reviewed.RESULTS:
Of 184 patients with CU, 43 patients (23.4%) had thyroid autoantibodies and 26 patients (14.1%) had thyroid dysfunction. While none of the five patients with Graves' disease showed any improvement of urticaria after treatment with anti-thyroid drugs, two of the 10 patients with Hashimoto's thyroiditis showed improved urticaria after being treated with levothyroxine.CONCLUSION:
Although levothyroxine treatment was effective in a minority of patients with CU, there may be a causal relationship between CU and thyroid autoimmunity.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Autoanticorpos
/
Doenças da Glândula Tireoide
/
Glândula Tireoide
/
Tireoidite
/
Tiroxina
/
Urticária
/
Autoimunidade
/
Doença de Graves
/
Prontuários Médicos
Tipo de estudo:
Estudo diagnóstico
Limite:
Humanos
Idioma:
Inglês
Revista:
Annals of Dermatology
Ano de publicação:
2016
Tipo de documento:
Artigo
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