A Case of Regional Metastatic Squamous Cell Carcinoma that Developed from Recurrent Chalazion

ABSTRACT

Squamous cell carcinoma is relatively rare in the eyelid, accounting for about 9.2% of all eyelid malignancy. Squamous cell carcinoma occurs most commonly in fair-skinned, elderly individuals who have had a history of chronic sun exposure and skin damage. This potentially lethal neoplasm is capable of metastasis to regional lymph nodes. Squamous cell carcinoma may arise de novo or from pre-existing lesions and also develop following radiation therapy. Various treatment modalities have been advocated including surgical extirpation with histologic control, radiation therapy and cryotherapy. We report this case of regional metastatic squamous cell carcinoma that developed from recurrent chalazion in 37 years old woman with a brief review of literetures.