Study on Causes of Respiratory Disease to the Middle East Respiratory Syndrome-negative Subjects
Journal of Bacteriology and Virology
;
: 156-164, 2017.
Artigo
em Coreano
| WPRIM
| ID: wpr-139529
ABSTRACT
Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe cases of human respiratory disease. The current outbreak of infection with this virus in South Korea, which began on May 20, 2015, has infected 186 patients and caused 36 deaths within 2 months. In this study, to investigate the viral pathogen causing acute respiratory infections, multiplex/RT-PCR was performed on were obtained from nucleic acid of the Middle East Respiratory Syndrome-negative subjects. Viruses and atypical bacteria were detected in 39 of 337 (11.6%). Frequent viruses were human rhinovirus (n=11, 3.3%), human metapneumovirus (n=9, 2.7%), parainfluenza (n=9, 2.7%) and adenovirus (n=4, 1.2%). Mycoplasma pneumonia (M. pneumonia) was detected in 1.8 % (n=6). Out of 9 human metapneumovirus (hMPV) positive samples, 6 samples were successfully sequenced using F gene. And M. pneumoniae was sequencing of a repetitive region of the P1 gene. Phylogenetic analysis revealed that hMPV clustered into A2b lineage (n=4), B2 lineage (n=2) and M. pneumoniae clustered into two genotypes Type 1 (n=4), Type 2a (n=2).
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Pneumonia
/
Pneumonia por Mycoplasma
/
Infecções Respiratórias
/
Rhinovirus
/
Bactérias
/
Sequências Repetitivas de Ácido Nucleico
/
Adenoviridae
/
Infecções por Paramyxoviridae
/
Metapneumovirus
/
Coronavírus da Síndrome Respiratória do Oriente Médio
Tipo de estudo:
Estudo de etiologia
Limite:
Humanos
País/Região como assunto:
Ásia
Idioma:
Coreano
Revista:
Journal of Bacteriology and Virology
Ano de publicação:
2017
Tipo de documento:
Artigo
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