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Deep Brain Stimulation: Technology at the Cutting Edge
Journal of Clinical Neurology ; : 167-182, 2010.
Artigo em Inglês | WPRIM | ID: wpr-139701
ABSTRACT
Deep brain stimulation (DBS) surgery has been performed in over 75,000 people worldwide, and has been shown to be an effective treatment for Parkinson's disease, tremor, dystonia, epilepsy, depression, Tourette's syndrome, and obsessive compulsive disorder. We review current and emerging evidence for the role of DBS in the management of a range of neurological and psychiatric conditions, and discuss the technical and practical aspects of performing DBS surgery. In the future, evolution of DBS technology may depend on several key areas, including better scientific understanding of its underlying mechanism of action, advances in high-spatial resolution imaging and development of novel electrophysiological and neurotransmitter microsensor systems. Such developments could form the basis of an intelligent closed-loop DBS system with feedback-guided neuromodulation to optimize both electrode placement and therapeutic efficacy.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Doença de Parkinson / Tremor / Encéfalo / Síndrome de Tourette / Neurotransmissores / Estimulação Encefálica Profunda / Depressão / Distonia / Eletrodos / Epilepsia Idioma: Inglês Revista: Journal of Clinical Neurology Ano de publicação: 2010 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Doença de Parkinson / Tremor / Encéfalo / Síndrome de Tourette / Neurotransmissores / Estimulação Encefálica Profunda / Depressão / Distonia / Eletrodos / Epilepsia Idioma: Inglês Revista: Journal of Clinical Neurology Ano de publicação: 2010 Tipo de documento: Artigo