Dedifferentiated Extraskeletal Myxoid Chondrosarcoma of the Masticator Space: A Case Report
Korean Journal of Pathology
;
: S101-S105, 2011.
Artigo
em Inglês
| WPRIM
| ID: wpr-140939
ABSTRACT
We describe a 69-year-old woman who presented with a dedifferentiated extraskeletal myxoid chondrosarcoma arising in the left masticator space. Computed tomography and magnetic resonance imaging revealed a 5 cm sized mass in the left masticator space. Histologically, the tumor consisted of two distinct areas. The less cellular area was a low-grade extraskeletal myxoid chondrosarcoma, composed of strands or cords of uniform spindle cells and abundant myxoid stroma. The more cellular, dedifferentiated area corresponded to a high grade myxofibrosarcoma, consisting of anaplastic tumor cells in myxoid stroma and geographic necrosis. The tumor cells of the former area were positive for S-100 protein, microtubule-associated protein-2 (MAP-2) and class III beta-tubulin, but negative for cytokeratin, smooth muscle actin, and desmin. The tumor cells in the latter, pleomorphic area showed MAP-2 and beta-tubulin immunoreactivity with a high Ki-67 labeling index. Based on its histologic and immunohistochemical features, the tumor was considered a dedifferentiated extraskeletal myxoid chondrosarcoma.
Texto completo:
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Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Tubulina (Proteína)
/
Imageamento por Ressonância Magnética
/
Proteínas S100
/
Condrossarcoma
/
Actinas
/
Desmina
/
Desdiferenciação Celular
/
Queratinas
/
Músculo Liso
/
Necrose
Limite:
Idoso
/
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Korean Journal of Pathology
Ano de publicação:
2011
Tipo de documento:
Artigo
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