Serum Bisphenol A Concentration in Postmenopausal Women with Osteoporosis
Journal of Bone Metabolism
;
: 87-93, 2012.
Artigo
em Inglês
| WPRIM
| ID: wpr-14166
ABSTRACT
OBJECTIVES:
Bishphenol A (BPA) is a representative endocrine disruptor and is also known as a xenoestrogen. The objective of the present study is to investigate how many patients are exposed to BPA and to analyze the relationships between serum BPA concentration, bone mineral density (BMD) and biochemical bone markers in postmenopausal women with osteoporosis.METHODS:
Total 51 patients were enrolled for measuring BPA and clinical variables including BMD and bone markers. The relationship between BPA and clinical variables were analyzed by the Pearson's correlation test and the Kruskal-Wallis test. Serum BPA concentration was measured by enzyme linked immunosorbent assay (ELISA).RESULTS:
BPA was detected in all samples. The mean BPA concentration was 1.44 +/- 0.52 ng/mL. There was no statistically significant correlation between BPA and clinical variables.CONCLUSION:
There was no statistical significance between serum BPA concentration and clinical variables related to bone metabolism. To clarify the effect of BPA on bone metabolism, further large scaled and high risk group investigation may be needed.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Osteoporose
/
Fenóis
/
Compostos Benzidrílicos
/
Ensaio de Imunoadsorção Enzimática
/
Densidade Óssea
Limite:
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Journal of Bone Metabolism
Ano de publicação:
2012
Tipo de documento:
Artigo
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