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Association of acute tubular necrosis with gross hematuria in cirrhosis-related immunoglobulin A nephropathy
Kidney Research and Clinical Practice ; : 43-46, 2013.
Artigo em Inglês | WPRIM | ID: wpr-142104
ABSTRACT
Immunoglobulin A (IgA) nephropathy associated with cirrhosis is the most common form of secondary IgA nephropathy (IgAN). Cirrhosis-related IgAN is usually clinically silent with a rare occurrence of gross hematuria, unlike in cases of idiopathic IgAN. Especially, acute tubular necrosis (ATN) associated with gross hematuria is very rare in cirrhosis-related IgAN, although acute renal failure is a frequently reported complication in advanced cirrhosis. Herein, we report an unusual case of ATN requiring renal replacement therapy, associated with gross hematuria in a patient with nonalcoholic, hepatitis B virus-associated cirrhosis. Results of a histopathological analysis revealed obstruction of the lumen of renal tubules by red blood cell casts, a marked tubular necrosis, and IgA deposition in the mesangium. The patient's renal function and gross hematuria were clearly improved after lamivudine treatment.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Fibrose / Imunoglobulina A / Imunoglobulinas / Terapia de Substituição Renal / Lamivudina / Eritrócitos / Insuficiência Renal / Injúria Renal Aguda / Glomerulonefrite por IGA / Hematúria Limite: Humanos Idioma: Inglês Revista: Kidney Research and Clinical Practice Ano de publicação: 2013 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Fibrose / Imunoglobulina A / Imunoglobulinas / Terapia de Substituição Renal / Lamivudina / Eritrócitos / Insuficiência Renal / Injúria Renal Aguda / Glomerulonefrite por IGA / Hematúria Limite: Humanos Idioma: Inglês Revista: Kidney Research and Clinical Practice Ano de publicação: 2013 Tipo de documento: Artigo