Small Flat Adenocarcinoma of the Colon Arising From Familial Adenomatous Polyposis Patient: Suggesting de novo Origin
Journal of the Korean Society of Coloproctology
;
: 655-660, 1998.
Artigo
em Coreano
| WPRIM
| ID: wpr-14364
ABSTRACT
Most adenocarcinomas of the colorectum arise in a visible benign precursor lesion, the adenoma, which is a monoclonal proliferation of dysplastic nonmalignant epithelial cells. Adenoma-adenocarcinoma sequence has been represented as the predominat pathogenetic pathway. But a small flat depressed colon cancer is characterized by non-polypoid growth pattem with no association of adenomatous tissues, which has tendency to early submucosal invasion and lymph node metastasis even in very small lesion (<10 mm). It supports de novo carcinogenesis of colorectal cancer, although most colorectal cancerarise in pre-existing adenoma. We report a case of small float colon adenocarcinoma arising in normal colonic epithelium rather than adenomatous polyp in familial adenomatous polyposis syndrome.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Neoplasias Colorretais
/
Adenocarcinoma
/
Adenoma
/
Colo
/
Neoplasias do Colo
/
Pólipos Adenomatosos
/
Polipose Adenomatosa do Colo
/
Células Epiteliais
/
Epitélio
/
Carcinogênese
Limite:
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Society of Coloproctology
Ano de publicação:
1998
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS