A Case of Periocular Capillary Hemangiomas Treated With Propranolol as a Single Therapy

ABSTRACT

PURPOSE: To report a case of periorbital infantile capillary hemangioma treated with propranolol as a single therapy. CASE SUMMARY: A 3-month-old girl with a growing red-purple mass on the right lower eyelid visited our clinic. The patient was diagnosed with capillary hemagioma by imaging studies. The mass had grown rapidly, and the visual axis was obscured in the follow-up. Oral propranolol therapy was initiated at a starting dose of 0.17 mg/kg at 8-hour intervals. After 2 doses, the propranolol was doubled, and after another 2 doses, the daily dose of 0.67 mg/kg divided into 3 was maintained. Three days after the initiation of the treatment, the color of the hemangioma had changed from red-purple to light purple, and the hemangioma had softened. The hemangioma continued to respond well with no side effects in the following 10 months. CONCLUSIONS: The authors suggest that oral propranolol treatment as a possibility of an effective and safe option for the vision-threatening periorbital capillary hemangioma as a single therapy.