Increased Risk of Asymptomatic Gallstones in Patients With Ulcerative Colitis
Intestinal Research
;
: 122-127, 2015.
Artigo
em Inglês
| WPRIM
| ID: wpr-144352
ABSTRACT
BACKGROUND/AIMS:
The relationship between Crohn's disease and gallstones is established. However, the prevalence and risk factors for gallstones in patients with ulcerative colitis (UC) are not yet well understood. The aim of this study was to evaluate the prevalence and risk factors of gallstones in patients with UC.METHODS:
This study was a retrospective single center study. A total of 87 patients with UC and 261 healthy controls were enrolled. Age, sex, and body mass index were matched. To investigate risk factors, the extent of UC, duration of disease, number of hospital admissions, and number of steroid treatments in patients with UC were evaluated.RESULTS:
The prevalence of gallstones in patients with UC was 13.8%, whereas that in healthy controls was only 3.1% (P or =50 years of age had a 3.6-times higher risk of gallstones compared to that in those <50 years of age, and the difference was statistically significant (odds ratio, 3.60; confidence interval, 1.03-12.61) in univariate analysis. There were no statistically significant disease-related risk factors for gallstones in UC patients.CONCLUSIONS:
This is the first study of gallstone prevalence in Korean UC patients. In this study, patients with UC had a higher prevalence of gallstones compared to that in well-matched healthy controls. Age seemed to be a possible risk factor, and more studies are needed. Further prospective, large-scale studies will be required to confirm the risk factors for gallstones in UC patients.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Colite Ulcerativa
/
Doença de Crohn
/
Cálculos Biliares
/
Índice de Massa Corporal
/
Prevalência
/
Estudos Retrospectivos
/
Fatores de Risco
/
Doenças Assintomáticas
Tipo de estudo:
Estudo de etiologia
/
Estudo observacional
/
Estudo de prevalência
/
Fatores de risco
Limite:
Humanos
Idioma:
Inglês
Revista:
Intestinal Research
Ano de publicação:
2015
Tipo de documento:
Artigo
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